主题：Value computation in the human brain: its basis and contagious nature

报告人：Dr. Shinsuke Suzuki, Tohoku University

时间：2018年9月18日（周二），13:30-14:30

地点：北京大学王克桢楼1113会议室

摘要：

There is accumulating evidence to suggest that the brain represents the expected value or utility of options at the time of decision-making. However, much less is known about how it is that value signals are constructed. In the first part of my talk, I will discuss how valuations for food rewards are constructed in the brain. Using a food-based decision task combined with multivariate analysis of fMRI data, I will demonstrate that values of food items can be predicted from beliefs about constituent nutritive attributes of food, and that those attributes are represented in lateral orbitofrontal cortex (lOFC), suggesting a key role for lOFC in encoding the precursor representations subsequently used to compute integrated subjective values. In the second part, I will present a study trying to explore the contagions nature of human valuation under risk. Using fMRI combined with computational modeling of behavioral data, I will show that human preference for risk can be systematically altered by the act of observing others' risk-related decisions. Furthermore, the contagious behavioral shift is implemented via a neural representation of risk in the caudate nucleus. These findings provide a mechanistic account for how observation of others' behavior can modulate an individual's own valuation.