主题：Dynamic Mapping and Interfacing with the Brain
报告人：Bin He Ph.D.(美国匹兹堡卡内基梅隆大学生物医学工程系主任和讲座教授,电气和计算机工程 和神经科学教授)
时间：2019年6月11日，10:00
地点：中科院生物物理所 9 号楼 9501 会议室
摘要：
Brain activity is distributed over the 3-dimensional volume and evolves in time. Mapping spatio-temporal distribution of brain activation with high spatial resolution and high temporal resolution is of great importance for understanding the brain and aiding in the clinical diagnosis and management of brain disorders. Electrophysiological source imaging (ESI) from noninvasively recorded high density electroencephalogram (EEG) has played a significant role in advancing our ability to image brain function and dysfunction. We will discuss principles and current state of EEG-based ESI in localizing and imaging human brain activity with applications to seizure localization. Promising clinical results validated by intracranial recordings and surgical resection outcomes demonstrate the merits of noninvasive EEG-based ESI in mapping epileptogenic zones, aiding surgical treatment of intractable epilepsy. We will also discuss the merits and challenges of multimodal functional neuroimaging by integrating electrophysiological and hemodynamic measurements. Our work indicates that the BOLD functional MRI and EEG can be integrated in a principled way, leading to substantially enhanced spatiotemporal resolution for functional imaging of dynamic brain activation. Finally, we will discuss the colocalization of hemodynamic and electrophysiological signals, and discuss our recent progress in brain-computer interface, demonstrating that humans can control a quadcopter and robotic arm by “mind” from noninvasive EEG signals.
Biographical Sketch：
Bin He is Department Head and Trustee Professor of Biomedical Engineering at Carnegie Mellon University (CMU), Pittsburgh, USA. He is also a Professor of Electrical and Computer Engineering and Neuroscience at CMU. Dr. He has made significant research contributions to the fields of neuroengineering and biomedical imaging, including electrophysiological source imaging, multimodal neuroimaging, noninvasive brain-computer interface, and neuromodulation. He has received a number of awards including the IEEE Biomedical Engineering Award, the Academic Career Achievement Award from the IEEE Engineering in Medicine and Biology Society, the Established Investigator Award from the American Heart Association, among others. He is an elected Fellow of International Academy of Medical and Biological Engineering, IEEE, American Institute of Medical and Biological Engineering, and Biomedical Engineering Society. Dr. He served as a past President of the IEEE Engineering in Medicine and Biology Society, and Editor-in-Chief of IEEE Transactions on Biomedical Engineering during 2013-2018. Dr. He is the Chair of the International Academy of Medical and Biological Engineering, and a Member of NIH BRAIN Multi-Council Working Group.
邀请人：何生 研究员