李毓龙实验室在Science杂志在线发表了题为“A tool kit of highly selective and sensitive genetically encoded neuropeptide sensors”的研究论文,报道了一种通过在神经肽受体中嫁接由荧光报告模块和部分第三胞内环形成嵌合体的探针开发策略,高效可通用地开发了一系列神经肽荧光探针工具包。由此策略开发而出的SST和CRF探...
方方/王茜团队在Science China Life Sciences发表题为“Local field potentials, spiking activity, and receptive fields in human visual cortex”的研究论文。该文运用颅内微电极技术,在人类视皮层成功同步记录了视觉刺激诱发的局部场电位(local field potential, LFP)与单神...
王征课题组在《NeuroImage》在线发表题为“Metabolic and functional substrates of impulsive decision-making in individuals with heroin addiction after prolonged methadone maintenance treatment”的学术论文。该研究揭示了长期接受美沙酮治疗的海洛因...
罗冬根团队在Nature发表题为“A single photoreceptor splits perception and entrainment by cotransmission”的研究论文,报道了在果蝇中局部反差和整体亮度信号的分离可通过同一感光细胞同时释放两种递质来实现。
饶毅实验室在《Genetics》发表题为“Sleep need, the key regulator of sleep homeostasis, is both Indicated and controlled by phosphorylation of threonine 221 in salt inducible kinase 3”的研究论文,发现一个分子的单个位点的化学修饰同时是睡眠需求的监...
岳伟华课题组在《JAMA Network Open》发表了题为“Multigenetic pharmacogenomics-guided treatment vs treatment as usual among hospitalized men with schizophrenia: a randomized clinical trial”的研究论文。该研究经随机对照试验发现,MPGT选药策略的...
邹鹏课题组在PNAS杂志在线合作发表了最新研究成果“Orange/far-red hybrid voltage indicators with reduced phototoxicity enable reliable long-term imaging in neurons and cardiomyocytes”,合成光稳定性良好的环辛四烯(COT)修饰的花菁染料,搭配灵敏度优异的复合型膜电位探...
邹鹏课题组在《Cell Reports Methods》发表题为“Functional imaging-guided cell selection for evolving genetically encoded fluorescent indicators”的研究论文,报道了基于荧光成像的定向进化方法Faculae,实现了遗传编码远红色钙探针的多维度表型筛选与定向进化。
王韵课题组在《Cancer Letters》发表题为“CDYL knockdown reduces glioma development through an antitumor immune response in the tumor microenvironment”的研究论文。文章以胶质瘤最常见的组织细胞学类型星形胶质细胞瘤来源的临床样本组织和细胞系为研究对象,揭示了CDYL在胶质瘤发生发展...
方方课题组在《Current Biology》合作发表题为“Dyadic visual perceptual learning on orientation discrimination”的研究论文,运用功能磁共振脑成像与心理物理学实验,首次揭示了社会情境对于视觉知觉学习的促进作用以及相关的神经加工机制。